Neuropathology changed by 3- and 6-months low-level PM2.5 inhalation exposure in spontaneously hypertensive rats

Neuropathology changed by 3- and 6-months low-level PM2.5 inhalation exposure in spontaneously hypertensive rats

Abstract Background Epidemiological evidence has linked fine particulate matter (PM2.5) to neurodegenerative diseases; however, the toxicological evidence remains unclear. The objective of this study was to investigate the effects of PM2.5 on neuropathophysiology in a hypertensive animal model. We e...

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Main Authors: Hsiao-Chi Chuang, Hsin-Chang Chen, Pei-Jui Chai, Ho-Tang Liao, Chang-Fu Wu, Chia-Ling Chen, Ming-Kai Jhan, Hui-I Hsieh, Kuen-Yuh Wu, Ta-Fu Chen, Tsun-Jen Cheng
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Particle and Fibre Toxicology
Subjects:
Air pollution
Autophagy
Central nervous system toxicity
Particulate matter
Tau
Online Access:http://link.springer.com/article/10.1186/s12989-020-00388-6

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