Repeated porphyrin lipoprotein-based photodynamic therapy controls distant disease in mouse mesothelioma via the abscopal effect

Repeated porphyrin lipoprotein-based photodynamic therapy controls distant disease in mouse mesothelioma via the abscopal effect

While photodynamic therapy (PDT) can induce acute inflammation in the irradiated tumor site, a sustained systemic, adaptive immune response is desirable, as it may control the growth of nonirradiated distant disease. Previously, we developed porphyrin lipoprotein (PLP), a ∼20 nm nanoparticle photose...

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Bibliographic Details
Main Authors: Lou Jenny, Aragaki Masato, Bernards Nicholas, Kinoshita Tomonari, Mo Jessica, Motooka Yamoto, Ishiwata Tsukasa, Gregor Alexander, Chee Tess, Chen Zhenchian, Chen Juan, Kaga Kichizo, Wakasa Satoru, Zheng Gang, Yasufuku Kazuhiro
Format: Article
Language:English
Published: De Gruyter 2021-08-01
Series:Nanophotonics
Subjects:
immune response
immunotherapy
pd-1
photodynamic therapy
porphyrin
thoracic malignant tumor
Online Access:https://doi.org/10.1515/nanoph-2021-0241

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