Immunomodulatory effects of different intravenous immunoglobulin preparations in chronic lymphocytic leukemia

Abstract Hypogammaglobulinemia is the most frequently observed immune defect in chronic lymphocytic leukemia (CLL). Although CLL patients usually have low serum levels of all isotypes (IgG, IgM and IgA), standard immunoglobulin (Ig) preparations for replacement therapy administrated to these patient...

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Bibliographic Details
Main Authors: Ana Colado, Esteban Enrique Elías, Valeria Judith Sarapura Martínez, Gregorio Cordini, Pablo Morande, Fernando Bezares, Mirta Giordano, Romina Gamberale, Mercedes Borge
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92412-8