Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria

Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria

The C2 sulfonates taurine and isethionate are also present in the anaerobic mammalian gut, where they are converted into toxic H2S by sulfate and sulfite-reducing bacteria. Here the authors characterise the O2-sensitive enzyme IseG that catalyzes the C-S bond cleavage of isethionate and show that Is...

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Bibliographic Details
Main Authors: Meining Xing, Yifeng Wei, Yan Zhou, Jun Zhang, Lianyun Lin, Yiling Hu, Gaoqun Hua, Ankanahalli N. Nanjaraj Urs, Dazhi Liu, Feifei Wang, Cuixia Guo, Yang Tong, Mengya Li, Yanhong Liu, Ee Lui Ang, Huimin Zhao, Zhiguang Yuchi, Yan Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09618-8

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