Clusterin serum levels are elevated in patients with early rheumatoid arthritis and predict disease activity and treatment response

Abstract Clusterin (CLU) is a molecular chaperone that participates in a variety of biological processes. Recent studies indicate its possible involvement in the development of bone erosions and autoimmunity. The aim of this study was to investigate its serum concentrations in patients with early rh...

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Bibliographic Details
Main Authors: Tereza Kropáčková, Heřman Mann, Olga Růžičková, Olga Šléglová, Lucia Vernerová, Veronika Horváthová, Michal Tomčík, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90973-2