AMPA Receptor Auxiliary Proteins of the CKAMP Family

α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are assembled of four core subunits and several additional interacting proteins. Cystine-knot AMPA receptor-modulating proteins (CKAMPs) constitute a family of four proteins that influence the trafficking, subcellular loc...

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Main Author:	Jakob von Engelhardt
Format:	Article
Language:	English
Published:	MDPI AG 2019-03-01
Series:	International Journal of Molecular Sciences
Subjects:	AMPA receptor glutamate receptor auxiliary subunit synaptic function short-term plasticity long-term plasticity hippocampus lateral geniculate nucleus
Online Access:	https://www.mdpi.com/1422-0067/20/6/1460

id	doaj-227be3aa1ef64e8ab2ac48d4fa30e138
record_format	Article
spelling	doaj-227be3aa1ef64e8ab2ac48d4fa30e1382020-11-25T01:56:26ZengMDPI AGInternational Journal of Molecular Sciences1422-00672019-03-01206146010.3390/ijms20061460ijms20061460AMPA Receptor Auxiliary Proteins of the CKAMP FamilyJakob von Engelhardt0Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germanyα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are assembled of four core subunits and several additional interacting proteins. Cystine-knot AMPA receptor-modulating proteins (CKAMPs) constitute a family of four proteins that influence the trafficking, subcellular localization and function of AMPA receptors. The four CKAMP family members CKAMP39/shisa8, CKAMP44/shisa9, CKAMP52/shisa6 and CKAMP59/shisa7 differ in their expression profile and their modulatory influence on AMPA receptor function. In this review, I report about recent findings on the differential roles of CKAMP family members.https://www.mdpi.com/1422-0067/20/6/1460AMPA receptorglutamate receptorauxiliary subunitsynaptic functionshort-term plasticitylong-term plasticityhippocampuslateral geniculate nucleus
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Jakob von Engelhardt
spellingShingle	Jakob von Engelhardt AMPA Receptor Auxiliary Proteins of the CKAMP Family International Journal of Molecular Sciences AMPA receptor glutamate receptor auxiliary subunit synaptic function short-term plasticity long-term plasticity hippocampus lateral geniculate nucleus
author_facet	Jakob von Engelhardt
author_sort	Jakob von Engelhardt
title	AMPA Receptor Auxiliary Proteins of the CKAMP Family
title_short	AMPA Receptor Auxiliary Proteins of the CKAMP Family
title_full	AMPA Receptor Auxiliary Proteins of the CKAMP Family
title_fullStr	AMPA Receptor Auxiliary Proteins of the CKAMP Family
title_full_unstemmed	AMPA Receptor Auxiliary Proteins of the CKAMP Family
title_sort	ampa receptor auxiliary proteins of the ckamp family
publisher	MDPI AG
series	International Journal of Molecular Sciences
issn	1422-0067
publishDate	2019-03-01
description	α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are assembled of four core subunits and several additional interacting proteins. Cystine-knot AMPA receptor-modulating proteins (CKAMPs) constitute a family of four proteins that influence the trafficking, subcellular localization and function of AMPA receptors. The four CKAMP family members CKAMP39/shisa8, CKAMP44/shisa9, CKAMP52/shisa6 and CKAMP59/shisa7 differ in their expression profile and their modulatory influence on AMPA receptor function. In this review, I report about recent findings on the differential roles of CKAMP family members.
topic	AMPA receptor glutamate receptor auxiliary subunit synaptic function short-term plasticity long-term plasticity hippocampus lateral geniculate nucleus
url	https://www.mdpi.com/1422-0067/20/6/1460
work_keys_str_mv	AT jakobvonengelhardt ampareceptorauxiliaryproteinsoftheckampfamily
_version_	1724980180677558272

AMPA Receptor Auxiliary Proteins of the CKAMP Family

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