Identification of a bacteria-like ferrochelatase in Strongyloides venezuelensis, an animal parasitic nematode.

Heme is an essential molecule for vast majority of organisms serving as a prosthetic group for various hemoproteins. Although most organisms synthesize heme from 5-aminolevulinic acid through a conserved heme biosynthetic pathway composed of seven consecutive enzymatic reactions, nematodes are known...

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Bibliographic Details
Main Authors: Eiji Nagayasu, Sohta A Ishikawa, Shigeru Taketani, Gunimala Chakraborty, Ayako Yoshida, Yuji Inagaki, Haruhiko Maruyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3596385?pdf=render