Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain

<p>Abstract</p> <p>Tibia fracture in rats followed by cast immobilization leads to nociceptive, trophic, vascular and bone-related changes similar to those seen in Complex Regional Pain Syndrome (CRPS). Substance P (SP) mediated neurogenic inflammation may be responsible for some o...

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Bibliographic Details
Main Authors: Wei Tzuping, Guo Tian-Zhi, Li Wen-Wu, Hou Saiyun, Kingery Wade S, Clark John
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/9/1/181