Impact of Global Transcriptional Silencing on Cell Cycle Regulation and Chromosome Segregation in Early Mammalian Embryos

Impact of Global Transcriptional Silencing on Cell Cycle Regulation and Chromosome Segregation in Early Mammalian Embryos

The onset of an early development is, in mammals, characterized by profound changes of multiple aspects of cellular morphology and behavior. These are including, but not limited to, fertilization and the merging of parental genomes with a subsequent transition from the meiotic into the mitotic cycle...

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Bibliographic Details
Main Authors: Martin Anger, Lenka Radonova, Adela Horakova, Diana Sekach, Marketa Charousova
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
oocyte
embryo
cell cycle
translation
transcriptional repression
Online Access:https://www.mdpi.com/1422-0067/22/16/9073

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