Orf-I and Orf-II-Encoded Proteins in HTLV-1 Infection and Persistence

Orf-I and Orf-II-Encoded Proteins in HTLV-1 Infection and Persistence

The 3' end of the human T-cell leukemia/lymphoma virus type-1 (HTLV-1) genome contains four overlapping open reading frames (ORF) that encode regulatory proteins. Here, we review current knowledge of HTLV-1 orf-I and orf-II protein products. Singly spliced mRNA from orf-I encodes p12, which can...

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Bibliographic Details
Main Authors: Genoveffa Franchini, Cynthia A. Pise-Masison, Cody Buchmann, Maria Fernanda de Castro-Amarante, Heather Gold, Claudio Fenizia, Dustin Edwards
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Viruses
Subjects:
human T-cell leukemia/lymphoma virus type-1
HTLV-1
ORF-I
ORF-II
p8
p12
p13
p30
Online Access:http://www.mdpi.com/1999-4915/3/6/861/

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