Phosphorylation and Internalization of Lysophosphatidic Acid Receptors LPA1, LPA2, and LPA3.

The lysophosphatidic acid receptors LPA1, LPA2, and LPA3 were individually expressed in C9 cells and their signaling and regulation were studied. Agonist-activation increases intracellular calcium concentration in a concentration-dependent fashion. Phorbol myristate acetate markedly inhibited LPA1-...

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Bibliographic Details
Main Authors: Rocío Alcántara-Hernández, Aurelio Hernández-Méndez, Gisselle A Campos-Martínez, Aldo Meizoso-Huesca, J Adolfo García-Sáinz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4608732?pdf=render