Evolution of Structural and Functional Diversity of Spexin in Mammalian and Non-mammalian Vertebrate Species

Spexin (SPX) is a novel neuropeptide, which was first identified in the human genome using bioinformatics. Since then, orthologs of human SPX have been identified in mammalian and non-mammalian vertebrates. The mature sequence of SPX, NWTPQAMLYLKGAQ, is evolutionally conserved across vertebrate spec...

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Bibliographic Details
Main Authors: Chor Hong Lim, Megan You Min Lee, Tomoko Soga, Ishwar Parhar
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00379/full