Survival of detached cancer cells is regulated by movement of intracellular Na+,K+-ATPase

Survival of detached cancer cells is regulated by movement of intracellular Na+,K+-ATPase

Summary: Beginning of metastasis, cancer cells detach from the primary tumor and they can survive even under loss of anchorage; however, the detachment-elicited mechanisms have remained unknown. Here, we found that Na+,K+-ATPase α3-isoform (α3NaK) in human cancer cells is dynamically translocated fr...

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Bibliographic Details
Main Authors: Takuto Fujii, Takahiro Shimizu, Mizuki Katoh, Shushi Nagamori, Keiichi Koizumi, Junya Fukuoka, Yoshiaki Tabuchi, Akira Sawaguchi, Tomoyuki Okumura, Kazuto Shibuya, Tsutomu Fujii, Hiroshi Takeshima, Hideki Sakai
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Cell Biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221003801

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