N of 1 trials and the optimal individualisation of drug treatments: a systematic review protocol

Abstract Background Guidelines and evidence-based drug treatment recommendations are usually based on the results of clinical trials, which have limited generalisability in routine clinical settings due to their restrictive eligibility criteria. These trials are also conducted in ideal and rigorousl...

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Bibliographic Details
Main Authors: Weyinmi A. Demeyin, Julia Frost, Obioha C. Ukoumunne, Simon Briscoe, Nicky Britten
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Systematic Reviews
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13643-017-0479-6