Co-expression Network Approach Reveals Functional Similarities among Diseases Affecting Human Skeletal Muscle

Co-expression Network Approach Reveals Functional Similarities among Diseases Affecting Human Skeletal Muscle

Diseases affecting skeletal muscle exhibit considerable heterogeneity in intensity, etiology, phenotypic manifestation and gene expression. Systems biology approaches using network theory, allows for a holistic understanding of functional similarities amongst diseases. Here we propose a co-expressio...

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Bibliographic Details
Main Authors: Kavitha Mukund, Shankar Subramaniam
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Physiology
Subjects:
co-expression networks
functional module framework
bioenergetics
calcium signaling
skeletal muscle physiology
neuromuscular disease
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00980/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00980/full

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