Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes

Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes

<p>Abstract</p> <p>Background</p> <p>Osteoarthritis (OA) is characterized by the degradation of articular cartilage, marked by the breakdown of matrix proteins. Studies demonstrated the involvement of chemokines in this process, and some may potentially serve as diagnos...

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Bibliographic Details
Main Authors: Chao Pin-Zhir, Hsieh Ming-Shium, Cheng Chao-Wen, Lin Yung-Feng, Chen Chien-Ho
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Biomedical Science
Subjects:
osteoarthritis
chemokine
cartilage degradation
chondrocyte
MMP-3
eotaxin-1
Online Access:http://www.jbiomedsci.com/content/18/1/86

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