Simultaneous determination of moxifloxacin and H2 receptor antagonist in pharmaceutical dosage formulations by RP-HPLC: application to in vitro drug interactions

Simultaneous determination of moxifloxacin and H2 receptor antagonist in pharmaceutical dosage formulations by RP-HPLC: application to in vitro drug interactions

Simultaneous determination of moxifloxacin (MOX) and H2-antagonists was first time developed in bulk and formulations. Purospher STAR C18 (250 x 4.6 mm, 5 μm) column was used. The mobile phase (methanol: water: ACN, 60:45:5 v/v/v, pH 2.7) was delivered at a flow rate of 1.0 mL min-1, eluent was moni...

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Bibliographic Details
Main Authors: Najma Sultana, Mahwish Akhtar, Sana Shamim, Somia Gul, Muhammad Saeed Arayne
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2011-01-01
Series:Química Nova
Subjects:
moxifloxacin
H2 receptor antagonists
ANOVA
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000400022&lng=en&tlng=en

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