Activation of dynamin-related protein 1 - dependent mitochondria fragmentation and suppression of osteosarcoma by cryptotanshinone

Activation of dynamin-related protein 1 - dependent mitochondria fragmentation and suppression of osteosarcoma by cryptotanshinone

Abstract Background Discovering how to regulate mitochondrial function to reduce cancer growth holds great potential for future cancer therapy development. Here we explore the effects of cryptotanshinone (CPT), a natural product derived from Salvia miltiorrhiza, on mitochondria of osteosarcoma (OS)...

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Bibliographic Details
Main Authors: Jia-Hau Yen, Hung Sen Huang, Chia Ju Chuang, Sheng-Teng Huang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Cryptotanshinone (CPT)
Drp1
Mitochondria fragmentation
Osteosarcoma
Online Access:http://link.springer.com/article/10.1186/s13046-018-1008-8

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http://link.springer.com/article/10.1186/s13046-018-1008-8

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