Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion.
BACKGROUND:Insulin secretion is a complex and highly regulated process. It is well established that cytoplasmic calcium is a key regulator of insulin secretion, but how elevated intracellular calcium triggers insulin granule exocytosis remains unclear, and we have only begun to define the identities...
Main Authors: | Natalia Gustavsson, Xiaorui Wang, Yue Wang, Tingting Seah, Jun Xu, George K Radda, Thomas C Südhof, Weiping Han |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-11-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2976867?pdf=render |
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