Computational and genetic reduction of a cell cycle to its simplest, primordial components.

What are the minimal requirements to sustain an asymmetric cell cycle? Here we use mathematical modelling and forward genetics to reduce an asymmetric cell cycle to its simplest, primordial components. In the Alphaproteobacterium Caulobacter crescentus, cell cycle progression is believed to be contr...

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Bibliographic Details
Main Authors: Seán M Murray, Gaël Panis, Coralie Fumeaux, Patrick H Viollier, Martin Howard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-12-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24415923/?tool=EBI

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