Cellular and metabolic mechanisms of nutrient actions in immune function

Abstract Various nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell...

Full description

Bibliographic Details
Main Author: Philip Newsholme
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-021-00162-3
id doaj-223267103f3c47758d3df8cabfd4b288
record_format Article
spelling doaj-223267103f3c47758d3df8cabfd4b2882021-06-27T11:03:47ZengNature Publishing GroupNutrition & Diabetes2044-40522021-06-011111410.1038/s41387-021-00162-3Cellular and metabolic mechanisms of nutrient actions in immune functionPhilip Newsholme0Curtin Medical School Faculty of Health Sciences and Curtin Health Innovation Research Institute, Curtin UniversityAbstract Various nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell function and fate appear to be glucose, amino acids, fatty acids, and vitamin D. This perspective will describe recently published information describing the mechanism of action of prominent nutritional intervention agents where evidence exists as to their action and potency.https://doi.org/10.1038/s41387-021-00162-3
collection DOAJ
language English
format Article
sources DOAJ
author Philip Newsholme
spellingShingle Philip Newsholme
Cellular and metabolic mechanisms of nutrient actions in immune function
Nutrition & Diabetes
author_facet Philip Newsholme
author_sort Philip Newsholme
title Cellular and metabolic mechanisms of nutrient actions in immune function
title_short Cellular and metabolic mechanisms of nutrient actions in immune function
title_full Cellular and metabolic mechanisms of nutrient actions in immune function
title_fullStr Cellular and metabolic mechanisms of nutrient actions in immune function
title_full_unstemmed Cellular and metabolic mechanisms of nutrient actions in immune function
title_sort cellular and metabolic mechanisms of nutrient actions in immune function
publisher Nature Publishing Group
series Nutrition & Diabetes
issn 2044-4052
publishDate 2021-06-01
description Abstract Various nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell function and fate appear to be glucose, amino acids, fatty acids, and vitamin D. This perspective will describe recently published information describing the mechanism of action of prominent nutritional intervention agents where evidence exists as to their action and potency.
url https://doi.org/10.1038/s41387-021-00162-3
work_keys_str_mv AT philipnewsholme cellularandmetabolicmechanismsofnutrientactionsinimmunefunction
_version_ 1721358227456655360