Melatonin Suppresses Renal Cortical Fibrosis by Inhibiting Cytoskeleton Reorganization and Mitochondrial Dysfunction through Regulation of miR-4516

Melatonin Suppresses Renal Cortical Fibrosis by Inhibiting Cytoskeleton Reorganization and Mitochondrial Dysfunction through Regulation of miR-4516

Renal fibrosis, a major risk factor for kidney failure, can lead to chronic kidney disease (CKD) and is caused by cytoskeleton reorganization and mitochondrial dysfunction. In this study, we investigated the potential of melatonin treatment to reduce renal fibrosis by recovering the cytoskeleton reo...

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Bibliographic Details
Main Authors: Yeo Min Yoon, Gyeongyun Go, Chul Won Yun, Ji Ho Lim, Jun Hee Lee, Sang Hun Lee
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
melatonin
miR-4516
renal cortical fibrosis
TH1 cells
cytoskeleton reorganization
Online Access:https://www.mdpi.com/1422-0067/21/15/5323

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