Immunological and Functional Characterization of RhoGDI3 and Its Molecular Targets RhoG and RhoB in Human Pancreatic Cancerous and Normal Cells.

RhoGDI proteins have been implicated in several human cancers; changes in their expression levels have shown pro- or anti-tumorigenic effects. Pancreatic Ductal Adenocarcinoma (PDAC) is a complex pathology, with poor prognosis, and most patients die shortly after diagnosis. Efforts have been focused...

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Main Authors: Mercedes Piedad de León-Bautista, Maria Del Carmen Cardenas-Aguayo, Diana Casique-Aguirre, Manuel Almaraz-Salinas, Sara Parraguirre-Martinez, Angelica Olivo-Diaz, María Del Rocío Thompson-Bonilla, Miguel Vargas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5104321?pdf=render