Autophagy dysfunctions associated with cancer cells and their therapeutic implications
Genomic analysis of human cancers indicates that the loss or mutation of core autophagy related genes, (ATG) is uncommon, whereas oncogenic events that activate autophagy and lysosomal biogenesis have been identified. Several studies have demonstrated that autophagy plays a wide variety of physiolog...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332219305566 |