Autophagy dysfunctions associated with cancer cells and their therapeutic implications

Genomic analysis of human cancers indicates that the loss or mutation of core autophagy related genes, (ATG) is uncommon, whereas oncogenic events that activate autophagy and lysosomal biogenesis have been identified. Several studies have demonstrated that autophagy plays a wide variety of physiolog...

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Bibliographic Details
Main Authors: Aurelian Udristioiu, Delia Nica-Badea
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219305566