Ulinastatin reduces the resistance of liver cancer cells to epirubicin by inhibiting autophagy.

Ulinastatin reduces the resistance of liver cancer cells to epirubicin by inhibiting autophagy.

During chemotherapy, drug resistance caused by autophagy remains a major challenge to successful treatment of cancer patients. The purpose of this study is to show that ulinastatin (UTI), a trypsin inhibitor, could reduce the resistance of liver cancer cells to chemotherapeutic agent epirubicin (EPI...

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Bibliographic Details
Main Authors: Bin Song, Qi Bian, Cheng Hao Shao, Gang Li, An An Liu, Wei Jing, Rui Liu, Yi-Jie Zhang, Ying-Qi Zhou, Xian-Gui Hu, Gang Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376693?pdf=render

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