Effectiveness of Immune Checkpoint Inhibitors in Transplant Recipients with Progressive Multifocal Leukoencephalopathy

Antibodies against PD1 have been used to treat progressive multifocal leukoencephalopathy (PML), a rare brain disease caused by JC virus. We used these antibodies (nivolumab) to treat PML in 3 kidney transplant recipients. All died within 8 weeks of diagnosis. Hence, nivolumab did not improve PML ou...

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Bibliographic Details
Main Authors: Chloé Medrano, François Vergez, Catherine Mengelle, Stanislas Faguer, Nassim Kamar, Arnaud Del Bello
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2019-11-01
Series:Emerging Infectious Diseases
Subjects:
PML
Online Access:https://wwwnc.cdc.gov/eid/article/25/11/19-0705_article