Test Tube Tooth: The Next Big Thing

• Main Authors: Preeti Yadav, Mohammed Tahir, Harsh Yadav, Rakshit Sureka, Aarti Garg
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2016-06-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: bioengineering; odontogenesis; regeneration; stem cells
• Online Access: https://jcdr.net/articles/PDF/7901/16809_CE(RA1)_F(T)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf

Unlike some vertebrates and fishes, humans do not have the capacity for tooth regeneration after the loss of permanent teeth. Although artificial replacement with removable dentures, fixed prosthesis and implants is possible through advances in the field of prosthetic dentistry, it would be ideal to recreate a third set of natural teeth to replace lost dentition. For many years now, researchers in the field of tissue engineering have been trying to bioengineer dental tissues as well as whole teeth. In order to attain a whole tooth through dental engineering, that has the same or nearly same biological, mechanical and physical properties of a natural tooth, it’s necessary to deal with all the cells and tissues which are concerned with the formation, maintenance and repair of the tooth. In this article we review the steps involved in odontogenesis or organogenesis of a tooth and progress in the bioengineering of a whole tooth.