Threonine 89 Is an Important Residue of Profilin-1 That Is Phosphorylatable by Protein Kinase A.

OBJECTIVE:Dynamic regulation of actin cytoskeleton is at the heart of all actin-based cellular events. In this study, we sought to identify novel post-translational modifications of Profilin-1 (Pfn1), an important regulator of actin polymerization in cells. METHODOLOGY:We performed in vitro protein...

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Bibliographic Details
Main Authors: David Gau, William Veon, Xuemei Zeng, Nathan Yates, Sanjeev G Shroff, David R Koes, Partha Roy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4882052?pdf=render