Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

• Main Authors: Tahereh Seifi, Ali Reza Kamali
• Format: Article
• Language: English
• Published: Elsevier 2021-09-01
• Series: Medicine in Drug Discovery
• Subjects: Graphene; Carbon; Coronavirus; COVID-19; Surface interaction
• Online Access: http://www.sciencedirect.com/science/article/pii/S2590098621000208

Coronavirus disease-2019 has been one of the most challenging global epidemics of modern times with a large number of casualties combined with economic hardships across the world. Considering that there is still no definitive cure for the recent viral crisis, this article provides a review of nanomaterials with antiviral activity, with an emphasis on graphene and its derivatives, including graphene oxide, reduced graphene oxide and graphene quantum dots. The possible interactions between surfaces of such nanostructured materials with coronaviruses are discussed. The antiviral mechanisms of graphene materials can be related to events such as the inactivation of virus and/or the host cell receptor, electrostatic trapping and physico-chemical destruction of viral species. These effects can be enhanced by functionalization and/or decoration of carbons with species that enhances graphene-virus interactions. The low-cost and large-scale preparation of graphene materials with enhanced antiviral performances is an interesting research direction to be explored.