Elucidation of Transport Mechanism of Paeoniflorin and the Influence of Ligustilide, Senkyunolide I and Senkyunolide A on Paeoniflorin Transport through Mdck-Mdr1 Cells as Blood–Brain Barrier in Vitro Model

The objectives of the present investigation were to: (1) elucidate the transport mechanism of paeoniflorin (PF) across MDCK-MDR1 monolayers; and (2) evaluate the effect of ligustilide (LIG), senkyunolide I (SENI) and senkyunolide A (SENA) on the transport of PF through blood–brain barrier so as to e...

Full description

Bibliographic Details
Main Authors: Peng-Yi Hu, Dan Liu, Qin Zheng, Qing Wu, Yu Tang, Ming Yang
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/3/300