Topical treatment with SPHINGOLIPIDS and GLYCOSAMINOGLYCANS for canine atopic dermatitis

Topical treatment with SPHINGOLIPIDS and GLYCOSAMINOGLYCANS for canine atopic dermatitis

Abstract Background Skin barrier dysfunction plays a key role in atopic dermatitis (AD). This impairment is related to altered composition and metabolism of epidermal sphingolipids and a deficiency of ceramides. Glycosaminoglycans (GAGs), and especially hyaluronic acid, could be useful in the manage...

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Bibliographic Details
Main Authors: Rosanna Marsella, Sergi Segarra, Kim Ahrens, Cristina Alonso, Lluís Ferrer
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Veterinary Research
Subjects:
Epidermal sphingolipids
Atopic dermatitis
Hyaluronic acid
Sphingomyelin
Animal model
Online Access:http://link.springer.com/article/10.1186/s12917-020-02306-6

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