Optimization Manufacture of Virus- and Tumor-Specific T Cells

Although ex vivo expanded T cells are currently widely used in pre-clinical and clinical trials, the complexity of manufacture remains a major impediment for broader application. In this review we discuss current protocols for the ex vivo expansion of virus- and tumor-specific T cells and describe o...

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Bibliographic Details
Main Authors: Natalia Lapteva, Juan F. Vera
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.4061/2011/434392