Inhibition of the sodium-glucose co-transporter 2 in the elderly: clinical and mechanistic insights into safety and efficacy

Inhibition of the sodium-glucose co-transporter 2 in the elderly: clinical and mechanistic insights into safety and efficacy

SUMMARY The prevalence of type 2 diabetes mellitus (T2DM) in the elderly grew sharply over the last decade. Reduced insulin sensitivity and secretory capacity, weight gain, sarcopenia, and elevated adiposity are all common metabolic and body changes in the aging population that favor an increased ri...

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Bibliographic Details
Main Authors: Riobaldo Cintra, Filipe A Moura, Luis Sergio F de Carvalho, Joaquim Barreto, Marcos Tambascia, Roberto Pecoits-Filho, Andrei C. Sposito
Format: Article
Language:English
Published: Associação Médica Brasileira
Series:Revista da Associação Médica Brasileira
Subjects:
Transportador 2 de glucose-sódio/antagonistas e inibidores
Diabetes mellitus
Idoso
Eficácia
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302019000100070&lng=en&tlng=en

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