eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease.
Alzheimer's disease (AD) is the main cause of dementia in our increasingly aging population. The debilitating cognitive and behavioral symptoms characteristic of AD make it an extremely distressing illness for patients and carers. Although drugs have been developed to treat AD symptoms and to s...
Main Authors: | Andrew Bottley, Nicola M Phillips, Thomas E Webb, Anne E Willis, Keith A Spriggs |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-09-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2946912?pdf=render |
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