Hydroxyapatite - antibiotic applications in bone therapy

• Main Authors: R Mecu, D Cîrţînă, V Nănescu
• Format: Article
• Language: English
• Published: THOT Publishing House 2019-11-01
• Series: Journal of Research and Innovation for Sustainable Society
• Subjects: hydroxyapatite-antibiotic; nanocomposite; physicochemical characterization
• Online Access: http://jriss.4ader.ro/pdf/2019-02/16_JRISS_2-122-125.pdf

The aim of the current study is to prevent and reduce the number of bacterial infections in surgical implantation procedures. The hydroxyapatite is a calcium phosphate ceramic with important applications in the medicine and chemistry fields. The hydroxyapatite is a main mineral constituent of the hard tissues such as bones and teeth. The hydroxyapatite has remarkable properties including biocompatibility, bioactivity and ability to form a direct chemical bond with human hard tissues. Over the last decades, the biomedical orthopaedic and dentistry sectors have witnessed an unprecedented demand for a large variety and number of scaffolds, grafts, implants, and endo-prostheses. The increase in life expectancy, and the higher frequency of injuries and diseases are regarded as the main factors for this growing demand in orthopaedic and dental devices. The quality of life for millions of people has been drastically improved by using hydroxyapatite for bone repair and tissue regeneration. Recent findings in the realm of ion-substituted hydroxyapatite (HA) could pave the road towards significant developments in biomedicine, with an emphasis on a new generation of orthopaedic and dentistry applications, since such bioceramics are able to mimic the structural, compositional and mechanical properties of the bone mineral phase.