Chloroquine attenuates thymic stromal lymphopoietin production via suppressing caspase-1 signaling in mast cells

Thymic stromal lymphopoietin (TSLP) produced by mast cells is involved in allergic inflammation pathogenesis. Chloroquine (CQ) is known to be an anti-malarial drug; however, additional protective functions of CQ have been discovered. This study aims to clarify an anti-inflammatory effect of CQ throu...

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Bibliographic Details
Main Authors: Na-Ra Han, Seong-Gyu Ko, Phil-Dong Moon, Hi-Joon Park
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222100617X