Imaging Tumor Vasculature Noninvasively with Positron Emission Tomography and RGD Peptides Labeled with Copper 64 Using the Bifunctonal Chelates DOTA, Oxo-DO3A. and PCTA

Imaging Tumor Vasculature Noninvasively with Positron Emission Tomography and RGD Peptides Labeled with Copper 64 Using the Bifunctonal Chelates DOTA, Oxo-DO3A. and PCTA

Two novel bifunctional chelates, 3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1(15),11,13-triene-3,6,9-triacetic acid (PCTA) and 1-oxa-4,7,10-triazacyclododecane-4,7,10-triacetic acid (Oxo-DO3A), were found to radiolabel antibodies with copper 64 ( 64 Cu) well for positron emission tomography (PET). In...

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Bibliographic Details
Main Authors: Donald T.T. Yapp, Cara L. Ferreira, Rajanvir K. Gill, Eszter Boros, May Q. Wong, Derek Mandel, Paul Jurek, Garry E. Kiefer
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2013-06-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2012.00044

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