c-Src kinase is involved in the tyrosine phosphorylation and activity of SLC11A1 in differentiating macrophages.

Studies have demonstrated that the solute carrier family 11 member 1 (SLC11A1) is heavily glycosylated and phosphorylated in macrophages. However, the mechanisms of SLC11A1 phosphorylation, and the effects of phosphorylation on SLC11A1 activity remain largely unknown. Here, the tyrosine phosphorylat...

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Bibliographic Details
Main Authors: Yong Zhong Xu, Thusanth Thuraisingam, Cynthia Kanagaratham, Shao Tao, Danuta Radzioch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5933793?pdf=render