Revisiting the role of Dcc in visual system development with a novel eye clearing method
The Deleted in Colorectal Carcinoma (Dcc) receptor plays a critical role in optic nerve development. Whilst Dcc is expressed postnatally in the eye, its function remains unknown as Dcc knockouts die at birth. To circumvent this drawback, we generated an eye-specific Dcc mutant. To study the organiza...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/51275 |