A scalable system for production of functional pancreatic progenitors from human embryonic stem cells.

A scalable system for production of functional pancreatic progenitors from human embryonic stem cells.

Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will require the translation of proof-of-principle concepts into a scalable, controlled, and regulated cell manufacturing process. We have previously demonstrated that hESC can be directed to differentiate into pancr...

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Bibliographic Details
Main Authors: Thomas C Schulz, Holly Y Young, Alan D Agulnick, M Josephine Babin, Emmanuel E Baetge, Anne G Bang, Anindita Bhoumik, Igor Cepa, Rosemary M Cesario, Carl Haakmeester, Kuniko Kadoya, Jonathan R Kelly, Justin Kerr, Laura A Martinson, Amanda B McLean, Mark A Moorman, Janice K Payne, Mike Richardson, Kelly G Ross, Eric S Sherrer, Xuehong Song, Alistair Z Wilson, Eugene P Brandon, Chad E Green, Evert J Kroon, Olivia G Kelly, Kevin A D'Amour, Allan J Robins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3356395?pdf=render

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http://europepmc.org/articles/PMC3356395?pdf=render

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