Thrombospondin-1 production is enhanced by Porphyromonas gingivalis lipopolysaccharide in THP-1 cells.

Periodontitis is a chronic inflammatory disease caused by gram-negative anaerobic bacteria. Monocytes and macrophages stimulated by periodontopathic bacteria induce inflammatory mediators that cause tooth-supporting structure destruction and alveolar bone resorption. In this study, using a DNA micro...

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Bibliographic Details
Main Authors: Misa Gokyu, Hiroaki Kobayashi, Hiromi Nanbara, Takeaki Sudo, Yuichi Ikeda, Tomonari Suda, Yuichi Izumi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4264871?pdf=render