Experimental Therapy of Paracoccidioidomycosis Using P10-Primed Monocyte-Derived Dendritic Cells Isolated From Infected Mice

Experimental Therapy of Paracoccidioidomycosis Using P10-Primed Monocyte-Derived Dendritic Cells Isolated From Infected Mice

Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin American caused by the thermodimorphic fungi of the genus Paracoccidioides spp. Notably, a Th1 immune response is required to control PCM. In this context, dendritic cells (DCs) seem to be essential players in capture, processing and presen...

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Bibliographic Details
Main Authors: Leandro B. R. Silva, Cleison L. Taira, Lucas S. Dias, Ana C. O. Souza, Joshua D. Nosanchuk, Luiz R. Travassos, Carlos P. Taborda
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
paracoccidioidomycosis
dendritic cells
peptide P10
vaccine
monocyte-derived dendritic cells
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01727/full

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