Quantification of Alfacalcidol Tablets Dissolution Content by Chemical Derivatization and LC-MS

Application of liquid chromatography-mass spectrometry (LC-MS) in analyzing the content of alfacalcidol tablets dissolution faces big challenges due to the low amount of alfacalcidol in each tablet and the low ionization efficacy of the compound with electrospray ionization (ESI) or atmospheric-pres...

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Bibliographic Details
Main Authors: Yang Liu, Xi Chen, Song Yuan, Wanhui Liu, Lan He, Qingsheng Zhang
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2020/6201656