Large scale analysis of positional effects of single-base mismatches on microarray gene expression data
<p>Abstract</p> <p>Background</p> <p>Affymetrix GeneChips utilize 25-mer oligonucleotides probes linked to a silica surface to detect targets in solution. Mismatches due to single nucleotide polymorphisms (SNPs) can affect the hybridization between probes and targets. P...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-04-01
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Series: | BioData Mining |
Online Access: | http://www.biodatamining.org/content/3/1/2 |