Large scale analysis of positional effects of single-base mismatches on microarray gene expression data

<p>Abstract</p> <p>Background</p> <p>Affymetrix GeneChips utilize 25-mer oligonucleotides probes linked to a silica surface to detect targets in solution. Mismatches due to single nucleotide polymorphisms (SNPs) can affect the hybridization between probes and targets. P...

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Bibliographic Details
Main Authors: Duan Fenghai, Pauley Mark A, Spindel Eliot R, Zhang Li, Norgren Robert B
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BioData Mining
Online Access:http://www.biodatamining.org/content/3/1/2