Exploring the Therapeutic Composition and Mechanism of Jiang-Suan-Chu-Bi Recipe on Gouty Arthritis Using an Integrated Approach Based on Chemical Profile, Network Pharmacology and Experimental Support Using Molecular Cell Biology

Exploring the Therapeutic Composition and Mechanism of Jiang-Suan-Chu-Bi Recipe on Gouty Arthritis Using an Integrated Approach Based on Chemical Profile, Network Pharmacology and Experimental Support Using Molecular Cell Biology

BackgroundGouty arthritis is a common metabolic disease caused by long-term purine metabolic disorder and elevated serum uric acid. Jiang-Suan-Chu-Bi recipe (JSCBR), a traditional Chinese herbal formula prescribed according to utilization frequency and cluster analysis, has been clinically validated...

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Bibliographic Details
Main Authors: Nan Xiao, Jialin Qu, Shiyong He, Peng Huang, Yanling Qiao, Guangxing Li, Taowen Pan, Hua Sui, Lin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
Jiang-Suan-Chu-Bi recipe (JSCBR)
gouty arthritis
chemical profile
network pharmacology
NOD-like receptor signaling pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01626/full

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