Synchronous bilateral breast carcinomas with divergent radiographic presentations: Radiologic–pathologic correlation of invasive mucinous and ductal carcinomas

The differential diagnosis of well-circumscribed breast masses on imaging includes mostly benign tumors. A potential pitfall in diagnostic breast imaging is that 10–20% of malignancies appear as lesions with benign imaging characteristics. This report presents a case of synchronous bilateral breast...

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Main Authors: Lena Caron, Evelyn May, Ashley Cimino-Mathews
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Human Pathology: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214330014201210
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spelling doaj-215e465adb47482e8044bec18e4e48982020-11-24T21:54:36ZengElsevierHuman Pathology: Case Reports2214-33002015-09-0123636610.1016/j.ehpc.2015.02.004Synchronous bilateral breast carcinomas with divergent radiographic presentations: Radiologic–pathologic correlation of invasive mucinous and ductal carcinomasLena Caron0Evelyn May1Ashley Cimino-Mathews2Johns Hopkins University School of Medicine, Baltimore, MarylandJohns Hopkins Hospital Department of Radiology, Baltimore, MarylandJohns Hopkins Hospital Department of Pathology, Baltimore, MarylandThe differential diagnosis of well-circumscribed breast masses on imaging includes mostly benign tumors. A potential pitfall in diagnostic breast imaging is that 10–20% of malignancies appear as lesions with benign imaging characteristics. This report presents a case of synchronous bilateral breast masses, one of which demonstrated benign imaging characteristics (well circumscribed) and the second of which demonstrated suspicious imaging characteristics (spiculated and indistinct). After radiologic–pathologic correlation, it was found that the well-circumscribed mass of the right breast was an invasive mucinous carcinoma, and the spiculated indistinct mass of the left breast was an invasive ductal carcinoma. This highlights a possible hazard of diagnostic imaging in the setting of benign-appearing lesions, and underscores the importance of radiographic–pathologic correlation in the evaluation of breast masses.http://www.sciencedirect.com/science/article/pii/S2214330014201210Radiology-pathology correlationMucinous carcinomaDuctal carcinoma
collection DOAJ
language English
format Article
sources DOAJ
author Lena Caron
Evelyn May
Ashley Cimino-Mathews
spellingShingle Lena Caron
Evelyn May
Ashley Cimino-Mathews
Synchronous bilateral breast carcinomas with divergent radiographic presentations: Radiologic–pathologic correlation of invasive mucinous and ductal carcinomas
Human Pathology: Case Reports
Radiology-pathology correlation
Mucinous carcinoma
Ductal carcinoma
author_facet Lena Caron
Evelyn May
Ashley Cimino-Mathews
author_sort Lena Caron
title Synchronous bilateral breast carcinomas with divergent radiographic presentations: Radiologic–pathologic correlation of invasive mucinous and ductal carcinomas
title_short Synchronous bilateral breast carcinomas with divergent radiographic presentations: Radiologic–pathologic correlation of invasive mucinous and ductal carcinomas
title_full Synchronous bilateral breast carcinomas with divergent radiographic presentations: Radiologic–pathologic correlation of invasive mucinous and ductal carcinomas
title_fullStr Synchronous bilateral breast carcinomas with divergent radiographic presentations: Radiologic–pathologic correlation of invasive mucinous and ductal carcinomas
title_full_unstemmed Synchronous bilateral breast carcinomas with divergent radiographic presentations: Radiologic–pathologic correlation of invasive mucinous and ductal carcinomas
title_sort synchronous bilateral breast carcinomas with divergent radiographic presentations: radiologic–pathologic correlation of invasive mucinous and ductal carcinomas
publisher Elsevier
series Human Pathology: Case Reports
issn 2214-3300
publishDate 2015-09-01
description The differential diagnosis of well-circumscribed breast masses on imaging includes mostly benign tumors. A potential pitfall in diagnostic breast imaging is that 10–20% of malignancies appear as lesions with benign imaging characteristics. This report presents a case of synchronous bilateral breast masses, one of which demonstrated benign imaging characteristics (well circumscribed) and the second of which demonstrated suspicious imaging characteristics (spiculated and indistinct). After radiologic–pathologic correlation, it was found that the well-circumscribed mass of the right breast was an invasive mucinous carcinoma, and the spiculated indistinct mass of the left breast was an invasive ductal carcinoma. This highlights a possible hazard of diagnostic imaging in the setting of benign-appearing lesions, and underscores the importance of radiographic–pathologic correlation in the evaluation of breast masses.
topic Radiology-pathology correlation
Mucinous carcinoma
Ductal carcinoma
url http://www.sciencedirect.com/science/article/pii/S2214330014201210
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AT evelynmay synchronousbilateralbreastcarcinomaswithdivergentradiographicpresentationsradiologicpathologiccorrelationofinvasivemucinousandductalcarcinomas
AT ashleyciminomathews synchronousbilateralbreastcarcinomaswithdivergentradiographicpresentationsradiologicpathologiccorrelationofinvasivemucinousandductalcarcinomas
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