Antigen experience shapes phenotype and function of memory Th1 cells.

Primary and secondary (boosted) memory CD8 T cells exhibit differences in gene expression, phenotype and function. The impact of repeated antigen stimulations on memory CD4 T cells is largely unknown. To address this issue, we utilized LCMV and Listeria monocytogenes infection of mice to characteriz...

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Bibliographic Details
Main Authors: Aaruni Khanolkar, Matthew A Williams, John T Harty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3676405?pdf=render