Smoking cessation reverses DNA double-strand breaks in human mononuclear cells.

Smoking cessation reverses DNA double-strand breaks in human mononuclear cells.

OBJECTIVE:Cigarette smoking is a major risk factor for atherosclerotic cardiovascular disease, which is responsible for a significant proportion of smoking-related deaths. However, the precise mechanism whereby smoking induces this pathology has not been fully delineated. Based on observation of DNA...

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Main Authors: Mari Ishida, Takafumi Ishida, Satoshi Tashiro, Hitomi Uchida, Chiemi Sakai, Naoya Hironobe, Katsuya Miura, Yu Hashimoto, Koji Arihiro, Kazuaki Chayama, Yasuki Kihara, Masao Yoshizumi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4122368?pdf=render

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