Orientation of tyrosine side chain in neurotoxic Aβ differs in two different secondary structures of the peptide

Amyloid β (Aβ) peptide is present as a major component in amyloid plaque that is one of the hallmarks of Alzheimer's disease. The peptide contains a single tyrosine residue and Aβ has a major implication in the pathology of the disease progression. Current investigation revealed that the tyrosi...

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Bibliographic Details
Main Authors: Swagata Das, Supriya Das, Anupam Roy, Uttam Pal, Nakul C. Maiti
Format: Article
Language:English
Published: The Royal Society 2016-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.160112