The effect of acute administration of quinidine, dextromethorphan and combination of dextromethorphan/quinidine on pentylenetetrazole-induced clonic and tonic seizure thresholds in mice

Background: Dextromethorphan (DM) as a non-opioid anti-cough has neuroprotective effects. Combination of DM with quinidine decreases rapid metabolism of DM to dextrorphan (DX). This study aimed to examine the effects of acute administration of quinidine, DM and combination of dextromethorphan/quinid...

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Bibliographic Details
Main Authors: Hassan Jamali, Azhdar Heydari
Format: Article
Language:fas
Published: Kashan University of Medical Sciences and Health Services 2019-08-01
Series:Fiyz̤
Subjects:
Online Access:http://feyz.kaums.ac.ir/article-1-3818-en.html